Quercetin targets the interaction of calcineurin with LxVP-type motifs in immunosuppression

Calcineurin (CN) is a unique calcium/calmodulin (CaM)-activated serine/threonine phosphatase. To perform its diverse biological functions, CN communicates with many substrates and other proteins. In the physiological activation of T cells, CN acts through transcriptional factors belonging to the NFA...

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Bibliographic Details
Published in:Biochimie
Main Authors: Zhao, Yane, Zhang, Jin, Shi, Xiaoyu, Li, Jing, Wang, Rui, Song, Ruiwen, Wei, Qun, Cai, Huaibin, Luo, Jing
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141604/
https://ncbi.nlm.nih.gov/pubmed/27109380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2016.04.011
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