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DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends

The cellular response to DNA double-strand breaks (DSBs) is initiated by the Mre11–Rad50–Xrs2 (MRX) complex that has structural and catalytic functions. MRX association at DSBs is counteracted by Rif2, which is known to interact with Rap1 that binds telomeric DNA through two tandem Myb-like domains....

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Bonetti, Diego, Rinaldi, Carlo, Vertemara, Jacopo, Notaro, Marco, Pizzul, Paolo, Tisi, Renata, Zampella, Giuseppe, Longhese, Maria Pia
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049697/
https://ncbi.nlm.nih.gov/pubmed/31879780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz1203
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