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The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia

Leukemic stem cells are multipotent, self-renewing, highly proliferative cells that can withstand drug treatments. Although currently available treatments potentially destroy blast cells, they fail to eradicate leukemic progenitor cells completely. Aldehyde dehydrogenase and STAT3 are frequently up-...

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書誌詳細
出版年:Haematologica
主要な著者: Annageldiyev, Charyguly, Gowda, Krishne, Patel, Trupti, Bhattacharya, Priyanjali, Tan, Su-Fern, Iyer, Soumya, Desai, Dhimant, Dovat, Sinisa, Feith, David J., Loughran, Thomas P., Amin, Shantu, Claxton, David, Sharma, Arati
フォーマット: Artigo
言語:Inglês
出版事項: Ferrata Storti Foundation 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7049373/
https://ncbi.nlm.nih.gov/pubmed/31123028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.212886
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