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Maritoclax induces apoptosis in acute myeloid leukemia cells with elevated Mcl-1 expression
Acute myeloid leukemia (AML) is one of the deadliest leukemias for which there is an urgent and unmet need for the development of novel treatment strategies. Multiple drug resistance mechanisms mediate poor drug response and relapse in patients, and a selective Mcl-1 inhibitor has been speculated to...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4119075/ https://ncbi.nlm.nih.gov/pubmed/24842334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.29186 |
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