載入...
Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics
The UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH is an essential lipid A biosynthetic enzyme that is conserved in the majority of gram-negative bacteria. It has emerged as an attractive novel antibiotic target due to the recent discovery of an LpxH-targeting sulfonyl piperazine compound (r...
Na minha lista:
| 發表在: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2020
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7049123/ https://ncbi.nlm.nih.gov/pubmed/32041866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912876117 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|