Mesoscale All-Atom Influenza Virus Simulations Suggest New Substrate Binding Mechanism

[Image: see text] Influenza virus circulates in human, avian, and swine hosts, causing seasonal epidemic and occasional pandemic outbreaks. Influenza neuraminidase, a viral surface glycoprotein, has two sialic acid binding sites. The catalytic (primary) site, which also binds inhibitors such as osel...

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Detaylı Bibliyografya
Yayımlandı:ACS Cent Sci
Asıl Yazarlar: Durrant, Jacob D., Kochanek, Sarah E., Casalino, Lorenzo, Ieong, Pek U., Dommer, Abigail C., Amaro, Rommie E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2020
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048371/
https://ncbi.nlm.nih.gov/pubmed/32123736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b01071
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