Cargando...
Cryo-Electron Microscopy Structure of the αIIbβ3–Abciximab Complex
OBJECTIVE: The αIIbβ3 antagonist anti-platelet drug abciximab is the chimeric antigen-binding fragment (Fab) comprising the variable regions of murine mAb 7E3 and the constant domains of human IgG1 and light chain κ. Previous mutagenesis studies suggested that abciximab binds to the β3 C177-C184 spe...
Guardado en:
| Publicado en: | Arterioscler Thromb Vasc Biol |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7047619/ https://ncbi.nlm.nih.gov/pubmed/31969014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.313671 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|