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Hematopoietic cell-expressed endothelial nitric oxide protects the liver from insulin resistance
OBJECTIVE: Mice genetically deficient in endothelial nitric oxide synthase (Nos3(−/−)) have fasting hyperinsulinemia and hepatic insulin resistance, indicating the importance of Nos3 in maintaining metabolic homeostasis. Although the current paradigm holds that these metabolic effects are derived sp...
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| Veröffentlicht in: | Arterioscler Thromb Vasc Biol |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7047596/ https://ncbi.nlm.nih.gov/pubmed/31996027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.313648 |
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