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A Macrophage Sterol-Responsive Network Linked to Atherogenesis

Cholesteryl ester accumulation by macrophages is a critical early event in atherogenesis. To test the hypothesis that sterol loading promotes foam cell formation and vascular disease by perturbing a network of interacting proteins, we used a global approach to identify proteins that are differential...

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Detalhes bibliográficos
Main Authors: Becker, Lev, Gharib, Sina A., Irwin, Angela D., Wijsman, Ellen, Vaisar, Tomas, Oram, John F., Heinecke, Jay W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893224/
https://ncbi.nlm.nih.gov/pubmed/20142100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.01.003
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