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A toxin-antidote CRISPR gene drive system for regional population modification

Engineered gene drives based on a homing mechanism could rapidly spread genetic alterations through a population. However, such drives face a major obstacle in the form of resistance against the drive. In addition, they are expected to be highly invasive. Here, we introduce the Toxin-Antidote Recess...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Champer, Jackson, Lee, Esther, Yang, Emily, Liu, Chen, Clark, Andrew G., Messer, Philipp W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7046741/
https://ncbi.nlm.nih.gov/pubmed/32109227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14960-3
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