Molecular safeguarding of CRISPR gene drive experiments

CRISPR-based homing gene drives have sparked both enthusiasm and deep concerns due to their potential for genetically altering entire species. This raises the question about our ability to prevent the unintended spread of such drives from the laboratory into a natural population. Here, we experiment...

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Udgivet i:eLife
Main Authors: Champer, Jackson, Chung, Joan, Lee, Yoo Lim, Liu, Chen, Yang, Emily, Wen, Zhaoxin, Clark, Andrew G, Messer, Philipp W
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2019
Fag:
Genetics and Genomics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358215/
https://ncbi.nlm.nih.gov/pubmed/30666960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41439
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