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Molecular safeguarding of CRISPR gene drive experiments

CRISPR-based homing gene drives have sparked both enthusiasm and deep concerns due to their potential for genetically altering entire species. This raises the question about our ability to prevent the unintended spread of such drives from the laboratory into a natural population. Here, we experiment...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Champer, Jackson, Chung, Joan, Lee, Yoo Lim, Liu, Chen, Yang, Emily, Wen, Zhaoxin, Clark, Andrew G, Messer, Philipp W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6358215/
https://ncbi.nlm.nih.gov/pubmed/30666960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41439
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