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Protein−Nucleic Acid Conjugation with Sterol Linkers Using Hedgehog Autoprocessing
Hedgehog (Hh) precursor proteins contain an autoprocessing domain called HhC whose native function is protein cleavage and C-terminal glycine sterylation. The transformation catalyzed by HhC occurs in cis from a precursor protein and exhibits wide tolerance toward both sterol and protein substrates....
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| Publicat a: | Bioconjug Chem |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7045895/ https://ncbi.nlm.nih.gov/pubmed/31600061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.9b00550 |
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