Subverting Hedgehog Protein Autoprocessing by Chemical Induction of Paracatalysis

Hedgehog proteins, a family of vital cell signaling factors, are expressed in precursor form, which requires specialized autoprocessing, called cholesterolysis, for full biological activity. Cholesterolysis occurs in cis through the action of the precursor’s C-terminal enzymatic domain, HhC. In this...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Smith, Carl J., Wagner, Andrew G., Stagnitta, Robert T., Xu, Zihan, Pezzullo, John L., Giner, José-Luis, Xie, Jian, Covey, Douglas F., Wang, Chunyu, Callahan, Brian P.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031038/
https://ncbi.nlm.nih.gov/pubmed/32013401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00013
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker