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Systematic comparison of somatic variant calling performance among different sequencing depth and mutation frequency

In the past decade, treatments for tumors have made remarkable progress, such as the successful clinical application of targeted therapies. Nowadays, targeted therapies are based primarily on the detection of mutations, and next-generation sequencing (NGS) plays an important role in relevant clinica...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Chen, Zixi, Yuan, Yuchen, Chen, Xiaoshi, Chen, Jiayun, Lin, Shudai, Li, Xingsong, Du, Hongli
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044309/
https://ncbi.nlm.nih.gov/pubmed/32103116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60559-5
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