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Systematic comparison of somatic variant calling performance among different sequencing depth and mutation frequency

In the past decade, treatments for tumors have made remarkable progress, such as the successful clinical application of targeted therapies. Nowadays, targeted therapies are based primarily on the detection of mutations, and next-generation sequencing (NGS) plays an important role in relevant clinica...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Zixi, Yuan, Yuchen, Chen, Xiaoshi, Chen, Jiayun, Lin, Shudai, Li, Xingsong, Du, Hongli
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044309/
https://ncbi.nlm.nih.gov/pubmed/32103116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60559-5
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