HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells

HIV-1 infection is associated with heightened inflammation and excess risk of cardiovascular disease, cancer, and other complications. These pathologies persist despite antiretroviral therapy (ART). In two independent cohorts, we found that innate lymphoid cells (ILCs) were depleted in the blood and...

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Bibliografske podrobnosti
izdano v:Nat Immunol
Main Authors: Wang, Yetao, Lifshitz, Lawrence, Gellatly, Kyle, Vinton, Carol L., Busman-Sahay, Kathleen, McCauley, Sean, Vangala, Pranitha, Kim, Kyusik, Derr, Alan, Jaiswal, Smita, Kucukural, Alper, McDonel, Patrick, Hunt, Peter W., Greenough, Thomas, Houghton, JeanMarie, Somsouk, Ma, Estes, Jacob D., Brenchley, Jason M., Garber, Manuel, Deeks, Steven G., Luban, Jeremy
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7044076/
https://ncbi.nlm.nih.gov/pubmed/32066947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0593-9
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