Comparative analysis of immune cells reveals a conserved regulatory lexicon

Most well-characterized enhancers are deeply conserved. In contrast, genome-wide comparative studies of steady state systems showed that only a small fraction of active enhancers are conserved. To better understand conservation of enhancer activity we used a comparative genomics approach that integr...

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Detalhes bibliográficos
Publicado no:Cell Syst
Main Authors: Donnard, Elisa, Vangala, Pranitha, Afik, Shaked, McCauley, Sean, Nowosielska, Anetta, Kucukural, Alper, Tabak, Barbara, Zhu, Xiaopeng, Diehl, William, McDonel, Patrick, Yosef, Nir, Luban, Jeremy, Garber, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876141/
https://ncbi.nlm.nih.gov/pubmed/29454939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2018.01.002
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