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Reconstructing B-cell receptor sequences from short-read single-cell RNA sequencing with BRAPeS

RNA sequencing of single B cells provides simultaneous measurements of the cell state and its antigen specificity as determined by the B-cell receptor (BCR). However, to uncover the latter, further reconstruction of the BCR sequence is needed. We present BRAPeS (“BCR Reconstruction Algorithm for Pai...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Afik, Shaked, Raulet, Gabriel, Yosef, Nir
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709718/
https://ncbi.nlm.nih.gov/pubmed/31451449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900371
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