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High-resolution mapping of multiway enhancer promoter interactions regulating pathogen detection

Eukaryotic gene expression regulation involves thousands of distal regulatory elements. Understanding the quantitative contribution of individual enhancers to gene expression is critical for assessing the role of disease-associated genetic risk variants. Yet, we lack the ability to accurately link g...

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Опубликовано в: :Mol Cell
Главные авторы: Vangala, Pranitha, Murphy, Rachel, Quinodoz, Sofia A., Gellatly, Kyle, McDonel, Patrick, Guttman, Mitchell, Garber, Manuel
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7572724/
https://ncbi.nlm.nih.gov/pubmed/32991830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.09.005
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