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A31 ALTERED SMALL INTESTINAL EPITHELIAL HOMEOSTASIS AND CELL FATE DECISION UPON LOSS OF TRP53 IN KRT15+ INTESTINAL STEM CELLS

BACKGROUND: Intestinal homeostasis is mainly maintained by two groups of stem cells: Lgr5+ stem cells and reserve stem cells. Recently, we reported that Krt15+ cells are present in small intestinal and colon epithelia, and harbor self-renewal, multipotent and regenerative capacities. Initiation of s...

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Bibliografiske detaljer
Udgivet i:J Can Assoc Gastroenterol
Main Authors: Dubey, A, Giroux, V
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043651/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz047.030
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