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A149 TRP53 LOSS IN KRT15+ INTESTINAL STEM CELLS SEVERELY AFFECTS SECRETORY CELL FATE AND SELF-RENEWAL

BACKGROUND: Intestinal epithelium homeostasis is maintained by two main populations of stem cells: Lgr5+ and reserve stem cells. Under injury, cell plasticity has been observed in progenitor and differentiated cells. We recently reported that Krt15+ cells are present in small intestinal and colon ep...

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Detalhes bibliográficos
Publicado no:J Can Assoc Gastroenterol
Main Authors: Dubey, A, Gonneaud, A, Giroux, V
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958743/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwab002.147
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