Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating

Two principal stem cell pools orchestrate the rapid cell turnover in the intestinal epithelium. Rapidly cycling Lgr5+ stem cells are intercalated between the Paneth cells at the crypt base (CBCs) and injury-resistant reserve stem cells reside above the crypt base. The intermediate filament Keratin 1...

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Publicat a:Stem Cell Reports
Autors principals: Giroux, Véronique, Stephan, Julien, Chatterji, Priya, Rhoades, Ben, Wileyto, E. Paul, Klein-Szanto, Andres J., Lengner, Christopher J., Hamilton, Kathryn E., Rustgi, Anil K.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993649/
https://ncbi.nlm.nih.gov/pubmed/29805107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.04.022
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