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A83 INTESTINAL EPITHELIAL CELL STEMNESS AND DIFFERENTIATION ARE REGULATED BY THE HIPPO PATHWAY EFFECTOR YAP1

BACKGROUND: The high rate of cell turnover in the intestinal epithelium is supported by the LGR5(+) crypt base columnar (CBC) stem cells, which are located at the lower part of the gland. Among of the various factors and signals like Wnt and Notch, YAP1 (yes associated protein) also plays an importa...

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Publié dans:J Can Assoc Gastroenterol
Auteurs principaux: Fallah, S, Beaulieu, J
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043552/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz047.082
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