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A83 INTESTINAL EPITHELIAL CELL STEMNESS AND DIFFERENTIATION ARE REGULATED BY THE HIPPO PATHWAY EFFECTOR YAP1

BACKGROUND: The high rate of cell turnover in the intestinal epithelium is supported by the LGR5(+) crypt base columnar (CBC) stem cells, which are located at the lower part of the gland. Among of the various factors and signals like Wnt and Notch, YAP1 (yes associated protein) also plays an importa...

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Pubblicato in:J Can Assoc Gastroenterol
Autori principali: Fallah, S, Beaulieu, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043552/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwz047.082
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