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Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold

The scavenger receptor cysteine-rich (SRCR) family of proteins comprises more than 20 membrane-associated and secreted molecules. Characterised by the presence of one or more copies of the ∼110 amino-acid SRCR domain, this class of proteins have widespread functions as antimicrobial molecules, scave...

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Publicat a:Life Sci Alliance
Autors principals: Reichhardt, Martin P, Loimaranta, Vuokko, Lea, Susan M, Johnson, Steven
Format: Artigo
Idioma:Inglês
Publicat: Life Science Alliance LLC 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043408/
https://ncbi.nlm.nih.gov/pubmed/32098784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900502
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