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A Naturally-Occurring Transcript Variant of MARCO Reveals the SRCR Domain is Critical for Function

Macrophage receptor with collagenous structure (MARCO) is a Class A Scavenger Receptor (cA-SR) that recognizes and phagocytoses of a wide variety of pathogens. Most cA-SRs that contain a C-terminal Scavenger Receptor Cysteine Rich (SRCR) domain use the proximal collagenous domain to bind ligands. In...

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Detalhes bibliográficos
Publicado no:Immunol Cell Biol
Main Authors: Novakowski, Kyle E., Huynh, Angela, Han, SeongJun, Dorrington, Michael G., Yin, Charles, Tu, Zhongyuan, Pelka, Peter, Whyte, Peter, Guarné, Alba, Sakamoto, Kaori, Bowdish, Dawn M.E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980223/
https://ncbi.nlm.nih.gov/pubmed/26888252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2016.20
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