Human-Specific Mutations and Positively Selected Sites in MARCO Confer Functional Changes

Macrophage Receptor with COllagenous structure (MARCO) is a class A scavenger receptor that binds, phagocytoses, and modifies inflammatory responses to bacterial pathogens. Multiple candidate gene approach studies have shown that polymorphisms in MARCO are associated with susceptibility or resistanc...

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Bibliografiska uppgifter
I publikationen:Mol Biol Evol
Huvudupphovsmän: Novakowski, Kyle E, Yap, Nicholas V L, Yin, Charles, Sakamoto, Kaori, Heit, Bryan, Golding, G Brian, Bowdish, Dawn M E
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2018
Ämnen:
Discoveries
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850514/
https://ncbi.nlm.nih.gov/pubmed/29165618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msx298
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