Human-Specific Mutations and Positively Selected Sites in MARCO Confer Functional Changes

Macrophage Receptor with COllagenous structure (MARCO) is a class A scavenger receptor that binds, phagocytoses, and modifies inflammatory responses to bacterial pathogens. Multiple candidate gene approach studies have shown that polymorphisms in MARCO are associated with susceptibility or resistanc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Evol
Hauptverfasser: Novakowski, Kyle E, Yap, Nicholas V L, Yin, Charles, Sakamoto, Kaori, Heit, Bryan, Golding, G Brian, Bowdish, Dawn M E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Discoveries
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850514/
https://ncbi.nlm.nih.gov/pubmed/29165618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msx298
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