The salivary scavenger and agglutinin (SALSA) binds MBL and regulates the lectin pathway of complement in solution and on surfaces

The scavenger receptor cysteine-rich (SRCR) protein SALSA, also known as gp340, salivary agglutinin (SAG) and deleted in malignant brain tumor 1 (DMBT1), is a 340 kDa glycoprotein expressed on mucosal surfaces and secreted into several body fluids. SALSA binds to a broad variety of microbes and endo...

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Detalhes bibliográficos
Main Authors: Martin eParnov Reichhardt, Vuokko eLoimaranta, Steffen eThiel, Jukka eFinne, Seppo eMeri, Hanna eJarva
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012-07-01
Colecção:Frontiers in Immunology
Assuntos:
mucosal immunity
complement regulation
gp340
Lectin pathway
Mannan-binding lectin
salivary agglutinin
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00205/full
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