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Stochastic analysis of genetic feedback controllers to reprogram a pluripotency gene regulatory network

Cellular reprogramming is traditionally accomplished through an open loop (OL) control approach, wherein key transcription factors (TFs) are injected in cells to steer the state of the pluripotency (PL) gene regulatory network (GRN), as encoded by TFs concentrations, to the pluripotent state. Due to...

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Detalhes bibliográficos
Publicado no:Proc Am Control Conf
Main Authors: Bruno, Simone, Al-Radhawi, M. Ali, Sontag, Eduardo D., Del Vecchio, Domitilla
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043063/
https://ncbi.nlm.nih.gov/pubmed/32103851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.23919/acc.2019.8814355
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