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Multi-modality in gene regulatory networks with slow promoter kinetics

Phenotypical variability in the absence of genetic variation often reflects complex energetic landscapes associated with underlying gene regulatory networks (GRNs). In this view, different phenotypes are associated with alternative states of complex nonlinear systems: stable attractors in determinis...

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Udgivet i:PLoS Comput Biol
Main Authors: Ali Al-Radhawi, M., Del Vecchio, Domitilla, Sontag, Eduardo D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6396950/
https://ncbi.nlm.nih.gov/pubmed/30779734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006784
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