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Stochastic analysis of genetic feedback controllers to reprogram a pluripotency gene regulatory network

Cellular reprogramming is traditionally accomplished through an open loop (OL) control approach, wherein key transcription factors (TFs) are injected in cells to steer the state of the pluripotency (PL) gene regulatory network (GRN), as encoded by TFs concentrations, to the pluripotent state. Due to...

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Détails bibliographiques
Publié dans:Proc Am Control Conf
Auteurs principaux: Bruno, Simone, Al-Radhawi, M. Ali, Sontag, Eduardo D., Del Vecchio, Domitilla
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043063/
https://ncbi.nlm.nih.gov/pubmed/32103851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.23919/acc.2019.8814355
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