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Stochastic analysis of genetic feedback controllers to reprogram a pluripotency gene regulatory network

Cellular reprogramming is traditionally accomplished through an open loop (OL) control approach, wherein key transcription factors (TFs) are injected in cells to steer the state of the pluripotency (PL) gene regulatory network (GRN), as encoded by TFs concentrations, to the pluripotent state. Due to...

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Podrobná bibliografie
Vydáno v:Proc Am Control Conf
Hlavní autoři: Bruno, Simone, Al-Radhawi, M. Ali, Sontag, Eduardo D., Del Vecchio, Domitilla
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043063/
https://ncbi.nlm.nih.gov/pubmed/32103851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.23919/acc.2019.8814355
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