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Postzygotic mosaicism in cerebral cavernous malformation

BACKGROUND: Cerebral cavernous malformations (CCMs) can cause severe neurological morbidity but our understanding of the mechanisms that drive CCM formation and growth is still incomplete. Recent experimental data suggest that dysfunctional CCM3-deficient endothelial cell clones form cavernous lesio...

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Detalhes bibliográficos
Publicado no:J Med Genet
Main Authors: Rath, Matthias, Pagenstecher, Axel, Hoischen, Alexander, Felbor, Ute
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042965/
https://ncbi.nlm.nih.gov/pubmed/31446422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2019-106182
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