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Postzygotic mosaicism in cerebral cavernous malformation

BACKGROUND: Cerebral cavernous malformations (CCMs) can cause severe neurological morbidity but our understanding of the mechanisms that drive CCM formation and growth is still incomplete. Recent experimental data suggest that dysfunctional CCM3-deficient endothelial cell clones form cavernous lesio...

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Publicat a:J Med Genet
Autors principals: Rath, Matthias, Pagenstecher, Axel, Hoischen, Alexander, Felbor, Ute
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042965/
https://ncbi.nlm.nih.gov/pubmed/31446422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2019-106182
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