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Postzygotic mosaicism in cerebral cavernous malformation

BACKGROUND: Cerebral cavernous malformations (CCMs) can cause severe neurological morbidity but our understanding of the mechanisms that drive CCM formation and growth is still incomplete. Recent experimental data suggest that dysfunctional CCM3-deficient endothelial cell clones form cavernous lesio...

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Bibliografski detalji
Izdano u:J Med Genet
Glavni autori: Rath, Matthias, Pagenstecher, Axel, Hoischen, Alexander, Felbor, Ute
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7042965/
https://ncbi.nlm.nih.gov/pubmed/31446422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2019-106182
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