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Adjunctive sertraline in HIV-associated cryptococcal meningitis: a randomised, placebo-controlled, double-blind phase 3 trial

BACKGROUND: Identifying new antifungals for cryptococcal meningitis remains a priority given the inadequacy of current therapy. Sertraline has previously demonstrated in vitro and in vivo activity against Cryptococcus. We evaluated the efficacy of adjunctive sertraline for cryptococcal meningitis in...

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書誌詳細
出版年:Lancet Infect Dis
主要な著者: Rhein, Joshua, Huppler Hullsiek, Kathy, Tugume, Lillian, Nuwagira, Edwin, Mpoza, Edward, Evans, Emily E., Kiggundu, Reuben, Pastick, Katelyn A., Ssebambulidde, Kenneth, Akampurira, Andrew, Williams, Darlisha A., Bangdiwala, Ananta S., Abassi, Mahsa, Musubire, Abdu K., Nicol, Melanie R., Muzoora, Conrad, Meya, David B., Boulware, David R.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7041360/
https://ncbi.nlm.nih.gov/pubmed/31345462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(19)30127-6
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