Development of Potent Forchlorfenuron Analogs and Their Cytotoxic Effect in Cancer Cell Lines

Forchlorfenuron (FCF) is a synthetic plant cytokinin widely used in agriculture to promote fruit size, that paradoxically inhibits proliferation, migration, and invasion in human cancer cell lines. FCF has also been shown to affect HIF-1α and HER2, which are both known to play a crucial role in canc...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kim, Kyu Kwang, Singh, Rakesh K., Khazan, Negar, Kodza, Arif, Singh, Niloy A., Jones, Aaron, Sivagnanalingam, Umayal, Towner, Mary, Itamochi, Hiroaki, Turner, Rachael, Moore, Richard G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039965/
https://ncbi.nlm.nih.gov/pubmed/32094384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59824-4
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