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Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain
Glucose homeostasis and growth essentially depend on the hormone insulin engaging its receptor. Despite biochemical and structural advances, a fundamental contradiction has persisted in the current understanding of insulin ligand–receptor interactions. While biochemistry predicts two distinct insuli...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7039211/ https://ncbi.nlm.nih.gov/pubmed/31727777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201907210 |
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