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Ectodomain shedding of FLT3 ligand is mediated by TACE

FLT3 ligand (FLT3L) has diverse roles in the hematopoietic system, which include stimulating proliferation of hematopoietic precursors and development of natural killer cells and dendritic cells. FLT3L is initially synthesized as a membrane-bound protein, which must be cleaved to become a soluble gr...

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Bibliografski detalji
Glavni autori: Horiuchi, Keisuke, Morioka, Hideo, Takaishi, Hironari, Akiyama, Haruhiko, Blobel, Carl P., Toyama, Yoshiaki
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921975/
https://ncbi.nlm.nih.gov/pubmed/19494263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801931
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