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PQLC2 recruits the C9orf72 complex to lysosomes in response to cationic amino acid starvation
The C9orf72 protein is required for normal lysosome function. In support of such functions, C9orf72 forms a heterotrimeric complex with SMCR8 and WDR41 that is recruited to lysosomes when amino acids are scarce. These properties raise questions about the identity of the lysosomal binding partner of...
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| Publicado no: | J Cell Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7039192/ https://ncbi.nlm.nih.gov/pubmed/31851326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201906076 |
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