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PQLC2 recruits the C9orf72 complex to lysosomes in response to cationic amino acid starvation
The C9orf72 protein is required for normal lysosome function. In support of such functions, C9orf72 forms a heterotrimeric complex with SMCR8 and WDR41 that is recruited to lysosomes when amino acids are scarce. These properties raise questions about the identity of the lysosomal binding partner of...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Cell Biol |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Rockefeller University Press
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7039192/ https://ncbi.nlm.nih.gov/pubmed/31851326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201906076 |
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