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The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes

Nuclear pore complexes (NPCs) regulate all cargo traffic across the nuclear envelope. The transport conduit of NPCs is highly enriched in disordered phenylalanine/glycine-rich nucleoporins (FG-Nups), which form a permeability barrier of still elusive and highly debated molecular structure. Here we p...

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Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Celetti, Giorgia, Paci, Giulia, Caria, Joana, VanDelinder, Virginia, Bachand, George, Lemke, Edward A.
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039189/
https://ncbi.nlm.nih.gov/pubmed/31723007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201907157
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