The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes

Nuclear pore complexes (NPCs) regulate all cargo traffic across the nuclear envelope. The transport conduit of NPCs is highly enriched in disordered phenylalanine/glycine-rich nucleoporins (FG-Nups), which form a permeability barrier of still elusive and highly debated molecular structure. Here we p...

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Publicado en:J Cell Biol
Autores principales: Celetti, Giorgia, Paci, Giulia, Caria, Joana, VanDelinder, Virginia, Bachand, George, Lemke, Edward A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7039189/
https://ncbi.nlm.nih.gov/pubmed/31723007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201907157
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