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Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies
OBJECTIVE: Understanding the heterogeneous pathology in Alzheimer’s disease (AD) and related tauopathies is one of the most urgent and fundamental challenges facing the discovery of novel disease modifying therapies. Through monitoring ensembles of toxic and non-toxic tau oligomers spontaneously for...
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| Опубликовано в: : | Alzheimers Dement |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7038631/ https://ncbi.nlm.nih.gov/pubmed/31653529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2019.06.4954 |
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