Population Pharmacokinetics of Isoniazid, Pyrazinamide, and Ethambutol in Pregnant South African Women with Tuberculosis and HIV

Tuberculosis is an important cause of maternal morbidity, but little is known about the effects of pregnancy on antituberculosis drug concentrations. We developed population pharmacokinetic models to describe drug dispositions of isoniazid, pyrazinamide, and ethambutol in pregnant women with tubercu...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Abdelwahab, Mahmoud Tareq, Leisegang, Rory, Dooley, Kelly E., Mathad, Jyoti S., Wiesner, Lubbe, McIlleron, Helen, Martinson, Neil, Waja, Ziyaad, Letutu, Matebogo, Chaisson, Richard E., Denti, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038290/
https://ncbi.nlm.nih.gov/pubmed/31844002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01978-19
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