Population Pharmacokinetics of Isoniazid, Pyrazinamide, and Ethambutol in Pregnant South African Women with Tuberculosis and HIV

Tuberculosis is an important cause of maternal morbidity, but little is known about the effects of pregnancy on antituberculosis drug concentrations. We developed population pharmacokinetic models to describe drug dispositions of isoniazid, pyrazinamide, and ethambutol in pregnant women with tubercu...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Abdelwahab, Mahmoud Tareq, Leisegang, Rory, Dooley, Kelly E., Mathad, Jyoti S., Wiesner, Lubbe, McIlleron, Helen, Martinson, Neil, Waja, Ziyaad, Letutu, Matebogo, Chaisson, Richard E., Denti, Paolo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2020
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038290/
https://ncbi.nlm.nih.gov/pubmed/31844002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01978-19
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