Pharmacokinetics of Isoniazid, Pyrazinamide, and Ethambutol in Newly Diagnosed Pulmonary TB Patients in Tanzania

Exposure to lower-than-therapeutic levels of anti-tuberculosis drugs is likely to cause selection of resistant strains of Mycobacterium tuberculosis and treatment failure. The first-line anti-tuberculosis (TB) regimen consists of rifampicin, isoniazid, pyrazinamide, and ethambutol, and correct manag...

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Udgivet i:PLoS One
Main Authors: Denti, Paolo, Jeremiah, Kidola, Chigutsa, Emmanuel, Faurholt-Jepsen, Daniel, PrayGod, George, Range, Nyagosya, Castel, Sandra, Wiesner, Lubbe, Hagen, Christian Munch, Christiansen, Michael, Changalucha, John, McIlleron, Helen, Friis, Henrik, Andersen, Aase Bengaard
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621059/
https://ncbi.nlm.nih.gov/pubmed/26501782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141002
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