A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases

Multiple neurodegenerative diseases are characterized by aggregation of tau molecules. Adult humans express six isoforms of tau that contain either 3 or 4 microtubule binding repeats (3R or 4R tau). Different diseases involve preferential aggregation of 3R (e.g Pick disease), 4R (e.g. progressive su...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Metrick, Michael A., Ferreira, Natália do Carmo, Saijo, Eri, Kraus, Allison, Newell, Kathy, Zanusso, Gianluigi, Vendruscolo, Michele, Ghetti, Bernardino, Caughey, Byron
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036215/
https://ncbi.nlm.nih.gov/pubmed/32087764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-0887-z
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