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Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease
Alzheimer disease (AD) and chronic traumatic encephalopathy (CTE) involve the abnormal accumulation in the brain of filaments composed of both three-repeat (3R) and four-repeat (4R) (3R/4R) tau isoforms. To probe the molecular basis for AD’s tau filament propagation and to improve detection of tau a...
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| Publicado no: | Acta Neuropathol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6426988/ https://ncbi.nlm.nih.gov/pubmed/30570675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1947-3 |
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