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Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease

Alzheimer disease (AD) and chronic traumatic encephalopathy (CTE) involve the abnormal accumulation in the brain of filaments composed of both three-repeat (3R) and four-repeat (4R) (3R/4R) tau isoforms. To probe the molecular basis for AD’s tau filament propagation and to improve detection of tau a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Neuropathol
Egile Nagusiak: Kraus, Allison, Saijo, Eri, Metrick, Michael A., Newell, Kathy, Sigurdson, Christina J., Zanusso, Gianluigi, Ghetti, Bernardino, Caughey, Byron
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426988/
https://ncbi.nlm.nih.gov/pubmed/30570675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1947-3
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