Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease

Alzheimer disease (AD) and chronic traumatic encephalopathy (CTE) involve the abnormal accumulation in the brain of filaments composed of both three-repeat (3R) and four-repeat (4R) (3R/4R) tau isoforms. To probe the molecular basis for AD’s tau filament propagation and to improve detection of tau a...

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Bibliografiska uppgifter
I publikationen:Acta Neuropathol
Huvudupphovsmän: Kraus, Allison, Saijo, Eri, Metrick, Michael A., Newell, Kathy, Sigurdson, Christina J., Zanusso, Gianluigi, Ghetti, Bernardino, Caughey, Byron
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2018
Ämnen:
Original Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426988/
https://ncbi.nlm.nih.gov/pubmed/30570675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1947-3
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